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Pediatr Hematol Oncol. 1987;4(4):337-44.

Hyponatremia and renal sodium wasting in patients receiving cisplatinum.

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1
Institut Gustave Roussy, Villejuif, France.

Abstract

Three children with malignant solid tumors developed hyponatremia with renal sodium wasting associated with other signs of tubular dysfunction, such as hypokalemia or hypomagnesemia, a few days after cis-diammine dichloroplatinum (CDDP) administration. The normalization of serum electrolyte disturbances was obtained with increased parenteral intakes in fluids and electrolytes, and renal sodium wasting stopped by itself a few days later.

PMID:
3152940
[Indexed for MEDLINE]
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