Format

Send to

Choose Destination
Intractable Rare Dis Res. 2019 Aug;8(3):179-186. doi: 10.5582/irdr.2019.01073.

Narrow-band chirp and tone burst auditory brainstem response as an early indicator of synaptopathy in industrial workers exposed to occupational noise.

Author information

1
All India Institute of Speech and Hearing, Manasagangothri, Mysuru, India.

Abstract

This study aims at characterizing and comparing the findings of auditory brainstem response (ABR) using narrow-band chirp (NB-chirp) and tone burst (TB) for both latency and amplitude parameters among those exposed to occupational noise and to determine which among the two serves as a better indicator of noise-induced cochlear neuropathy. Forty adult males in the age range of 20-35 years were considered, wherein 20 of them were exposed to noise > 80 dB (A) for 8 hours per day constituting Noise-exposed group; and Control group consisted of 20 individuals without occupational noise exposure. ABR was recorded using NB-chirp and TB for four frequencies at 80 dB nHL through Etymotic Research - 3A (ER-3A) Insert phones using Interacoustics Eclipse EP-25 in individuals with and without noise exposure. MANOVA was performed to compare between TB ABR and NB-chirp ABR between the two groups. Statistical analysis revealed a notable difference for NB-chirp comparisons between the two groups at three frequencies: 500 Hz, F(1, 38) = 10.6; 1000 Hz, F(1, 38) = 7.91; and 2000 Hz, F(1, 38) = 6.64. Whereas, the difference was evident at only 500 Hz: F(1, 38) = 4.98 in case of TB ABR. However, there was no significant difference seen at any of the frequencies for amplitude parameters in both TB and NB-chirp ABR. Latency of wave V using NB-chirp was considered to be a better indicator compared to TB, acting as a better clinical tool in early identification, diagnosis, and monitoring of noise induced hearing loss (NIHL).

KEYWORDS:

Auditory brainstem response; cochlear synaptopathy; narrow band-chirp; noise induced hearing loss; tone burst

Supplemental Content

Full text links

Icon for IRCA-BSSA Group Icon for PubMed Central
Loading ...
Support Center