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Microbiol Resour Announc. 2019 Sep 12;8(37). pii: e00895-19. doi: 10.1128/MRA.00895-19.

Complete Genome Sequence of Herpes Simplex Virus 1 Strain MacIntyre.

Author information

1
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
2
Sequencing Facility, Center for Cancer Research, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.
3
Laboratory of Human Retrovirology and Immunoinformatics, Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA timamichi@mail.nih.gov.
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Contributed equally

Abstract

Herpes simplex virus type 1 (HSV-1) strain MacIntyre has a severe defect in the anterograde spread after replication in the nucleus. To better understand and identify the genetic determinants that lead to the unique phenotypes of the MacIntyre strain, we sequenced its genome with PacBio single-molecule real-time sequencing technology and resolved the complete sequence.

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