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Neurol India. 2019 Jul-Aug;67(4):1087-1089. doi: 10.4103/0028-3886.266293.

Longitudinally Extensive Transverse Myelitis with Aquaporin-4 Antibody Positivity in Renal Cell Carcinoma: Rare Occurrence.

Author information

1
Department of Neurology, MS Ramaiah Medical College and Hospital, Bangalore, Karnataka, India.

Abstract

The occurrence of longitudinally extensive transverse myelitis (LETM) in an elderly patient should evoke search for underlying systemic malignancy. Intramedullary spinal cord metastases and paraneoplastic myelopathy are the most common etiology for LETM in patients with systemic malignancy. The occurrence of LETM in association with renal cell carcinoma with aquaporin-4 (AQP4) antibody positivity has not been reported. We report an elderly woman who presented with acute paraplegia and was diagnosed as having LETM with AQP4 positivity and renal cell carcinoma.

KEYWORDS:

Antibody; aquaporin-4; renal cell carcinoma; transverse myelitis

PMID:
31512641
DOI:
10.4103/0028-3886.266293
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