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Ann Oncol. 2019 Sep 3. pii: mdz295. doi: 10.1093/annonc/mdz295. [Epub ahead of print]

Position of an international panel of lung cancer experts on the decision for expansion of approval for pembrolizumab in advanced non-small cell lung cancer with a PD-L1 expression level of ≥ 1% by the U.S. Food and Drug Administration.

Author information

1
Department of Medical Oncology, Henry Dunant Hospital Center, Athens, Greece.
2
Department of Medical Oncology, CIOCC HM Delfos Hospital, Barcelona, Spain.
3
Department of Oncology, University of Turin, AOU San Luigi, Orbassano, Italy.
4
Centre Hospitalier Universitaire de Montréal, University of Montreal, Montreal, Canada.
5
Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.
6
Division of Cancer Sciences, University of Manchester, Manchester, UK.
7
University Clinic Golnik, Medical Faculty Ljubljana, Slovenia.
8
Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht and Erasmus Medical Center, Rotterdam, The Netherlands.
9
Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA.
10
Soroka Medical Center and Ben-Gurion University, Beer-Sheva, Israel.
11
Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA.
12
Lung Clinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany.
13
Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA.
14
Division of Medical Oncology, National Cancer Centre, Singapore.
15
Respiratory Oncology Unit, University Hospital KU Leuven, Leuven, Belgium.
16
Department of Medical Oncology, City of Hope Comprehensive Cancer Center, California, USA.
17
Cancer Medicine Department, Institut Gustave Roussy, Villejuif, France.
18
Université Paris-Saclay, Orsay, France.

KEYWORDS:

KEYNOTE-042; PD-L1≥1%; non-small cell lung cancer; pembrolizumab

PMID:
31504132
DOI:
10.1093/annonc/mdz295

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