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Vaccine. 2019 Sep 6. pii: S0264-410X(19)31137-5. doi: 10.1016/j.vaccine.2019.08.061. [Epub ahead of print]

Summit proceedings: Biomedical countermeasure development for emerging vector-borne viral diseases.

Author information

1
Trudeau Institute, Saranac Lake, NY, USA.
2
Biological Technologies Office, Defense Advanced Research Projects Agency (DARPA), Arlington, VA, USA.
3
PATH, Washington, DC, USA.
4
Sealy Institute for Vaccine Sciences and Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA.
5
Sanofi Pasteur, Swiftwater, PA, USA.
6
Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
7
ICON Government and Public Health Solutions, Washington, D.C., USA.
8
Crozet BioPharma LLC, Devens, MA, USA.
9
Virology Branch, Division of Microbiology and Infectious Diseases, NIAID, NIH, Rockville, MD, USA.
10
International Vaccine Institute, Seoul, South Korea.
11
Coalition for Epidemic Preparedness Innovations (CEPI), London, UK.
12
Division of Infectious Diseases, State University of New York, Upstate Medical University, Syracuse, NY, USA.

Abstract

Emerging and re-emerging infectious diseases are an expanding global threat to public health, security, and economies. Increasing populations, urbanization, deforestation, climate change, anti-vaccination movements, war, and international travel are some of the contributing factors to this trend. The recent Ebola, MERS-CoV, and Zika outbreaks demonstrated we are insufficiently prepared to respond with proven safe and effective countermeasures (i.e., vaccines and therapeutics). The State University of New York Upstate Medical University and the Trudeau Institute convened a summit of key opinion and thought leaders in the life sciences and biomedical research and development enterprises to explore global biopreparedness challenges, take an inventory of existing capabilities and capacities related to preparation and response, assess current "gaps," and prospect what could be done to improve our position. Herein we describe the summit proceedings, "Translational Immunology Supporting Biomedical Countermeasure Development for Emerging Vector-borne Viral Diseases," held October 2-3, 2018, at the Trudeau Institute in Saranac Lake, NY.

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