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Nutrients. 2019 Sep 6;11(9). pii: E2136. doi: 10.3390/nu11092136.

Bisphenol A Analogues in Food and Their Hormonal and Obesogenic Effects: A Review.

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Department of Nutrition and Food Science, University of Granada, Campus of Cartuja, 18071 Granada, Spain.
Department of Analytical Chemistry, University of Granada, Campus of Fuentenueva, 18071 Granada, Spain.
Department of Legal Medicine and Toxicology, University of Granada, 18071 Granada, Spain.
Department of Biochemistry & Molecular Biology III, University of Granada, PTS, 18016 Granada, Spain.
GENYO, Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research, Av. de la Ilustración 114, 18016 Granada, Spain.
Department of Microbiology, Faculty of Pharmacy, University of Granada, Campus of Cartuja, 18071 Granada, Spain.
Instituto de Investigación Biosanitaria ibs, 18016 Granada, Spain.


Bisphenol A (BPA) is the most well-known compound from the bisphenol family. As BPA has recently come under pressure, it is being replaced by compounds very similar in structure, but data on the occurrence of these BPA analogues in food and human matrices are limited. The main objective of this work was to investigate human exposure to BPA and analogues and the associated health effects. We performed a literature review of the available research made in humans, in in vivo and in vitro tests. The findings support the idea that exposure to BPA analogues may have an impact on human health, especially in terms of obesity and other adverse health effects in children.


bisphenol A analogues; food; obesogenic effect

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