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Chemosphere. 2020 Jan;239:124701. doi: 10.1016/j.chemosphere.2019.124701. Epub 2019 Sep 3.

Concentrations and loadings of organophosphate and replacement brominated flame retardants in house dust from the home study during the PBDE phase-out.

Author information

1
Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
2
Virginia Institute of Marine Science, William and Mary, Gloucester Point, VA, USA.
3
Department of General Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
4
Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada.
5
Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA; School of Public Health, University of Nevada, Las Vegas, Las Vegas, NV, USA.
6
Imaging Research Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
7
Department of Epidemiology, Brown University, Providence, RI, USA.
8
Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH, USA. Electronic address: aimin.chen@uc.edu.

Abstract

Polybrominated diphenyl ethers, a class of flame retardants and endocrine disruptors, have been substituted in new products by organophosphate (OPFR) and replacement brominated flame retardants (RBFR). OPFRs and RBFRs readily migrate from consumer products into dust where humans are exposed via incidental ingestion and inhalation. We quantified concentrations and loadings of OPFRs and RBFRs in house dust samples (n = 317) collected from the homes of Cincinnati women between 2003 and 2006 and examined their associations with demographic and house characteristics. Tris-(1-chloro-2-propyl)-phosphate (TCIPP, geometric mean [GM]: 2140 ng g-1, range: 70.1-166,000 ng g-1), tris-(1,3-dichloro-2-propyl)-phosphate (TDCIPP, GM: 1840 ng g-1, range: 55.2-228,000 ng g-1), triphenyl phosphate (TPHP, GM: 1070 ng g-1, range: 34.1-62,100 ng g-1), 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (EH-TBB, GM: 59.5 ng g-1, range: 2.82-7800 ng g-1), and bis-(2-ethylhexyl)-tetrabromophthalate (BEH-TEBP, GM: 121 ng g-1, range 2.17-13,600 ng g-1) were all detected in >90% of dust samples; tris-(2-chloroethyl)-phosphate (TCEP, GM: 669 ng g-1, range: 56.8-160,000 ng g-1) was detected in 80.1% of samples. Concentrations of EH-TBB and BEH-TEBP increased in house dust from 2003 to 2006. The number of people living in the home, race, education, floor type, and year of sample collection were associated with some OPFR and RBFR concentrations and loadings. This study suggests that OPFRs and RBFRs were ubiquitous in house dust during the PBDE phase-out and justifies more research on the consequences of exposure to these environmental chemicals.

PMID:
31499316
PMCID:
PMC6854320
[Available on 2021-01-01]
DOI:
10.1016/j.chemosphere.2019.124701
[Indexed for MEDLINE]

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