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Dermatol Surg. 2019 Sep 2. doi: 10.1097/DSS.0000000000002105. [Epub ahead of print]

Microcannula Injection of Large Gel Particle Hyaluronic Acid for Cheek Augmentation and the Correction of Age-Related Midface Contour Deficiencies.

Author information

1
Skin Care and Laser Physicians of Beverly Hills, Los Angeles, California.
2
Hessler Plastic Surgery, Palo Alto, California.
3
Union Square Laser Dermatology, New York, New York.
4
Galderma Research and Development, LLC, Fort Worth, Texas.
5
Collaborative Medical Writing, LLC, El Campo, Texas.
6
Facial Plastic and Cosmetic Surgery Medical Corp, Beverly Hills, California.

Abstract

BACKGROUND:

There is a growing trend toward the use of blunt-tip microcannulas for the treatment of midface volume loss with injectable hyaluronic acid.

OBJECTIVE:

To evaluate the safety and efficacy of large gel particle hyaluronic acid with lidocaine, injected with a blunt-tip microcannula, for cheek augmentation and the correction of age-related midface contour deficiency.

MATERIALS AND METHODS:

Sixty subjects with mild to substantial loss of midface fullness were treated to optimal correction. Adverse events (AEs) were obtained during each examination visit. Efficacy was evaluated using the Global Aesthetic Improvement Scale, the Medicis Midface Volume Scale (MMVS), and the FACE-Q subject satisfaction questionnaire through 16 weeks.

RESULTS:

Five AEs were reported, with only one being considered injection procedure-related (mild presyncope). No serious AEs were reported. Global aesthetic improvements were reported for the majority of subjects (≥98.3% for investigator-assessed and ≥91.5% for subject-assessed) for up to 16 weeks. At 8 weeks, the MMVS responder rate was 100% and subject satisfaction scores (5/6 questions) in the FACE-Q were ≥91.5%.

CONCLUSION:

Hyaluronic acid with lidocaine, injected with a blunt-tip microcannula, has a favorable safety profile and is effective up to 16 weeks for cheek augmentation and the correction of age-related midface contour deficiencies (NCT03160716).

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