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J Med Primatol. 1988;17(5):235-46.

Non-A, non-B hepatitis-related hepatocellular carcinoma in a chimpanzee.

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Laboratory for Experimental Medicine and Surgery in Primates (LEMSIP) New York University Medical Center, Tuxedo 10987.


Epidemiology has indicated the possible association of non-A, non-B hepatitis (NANBH) with hepatocellular carcinoma (HCC) in man, but there are no means for confirmation. Chimpanzees are recognized models for studying hepatitis B and NANBH, and may become carriers of both. The first case of HCC to be reported in chimpanzees was found after longitudinal study of a hepatitis B-free chimpanzee 7 years after inoculation with human plasma from a patient reported to have chronic NANBH.

[Indexed for MEDLINE]

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