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Cancer Discov. 2019 Aug 30. doi: 10.1158/2159-8290.CD-NB2019-103. [Epub ahead of print]

Targeting WEE1 in Pancreatic Cancer.

[No authors listed]

Abstract

According to results from a phase I/II trial, the investigational WEE1 inhibitor adavosertib combined with gemcitabine and radiation is well tolerated and may benefit patients with locally advanced pancreatic adenocarcinoma by increasing both systemic and local disease control.

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