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Regen Med. 2019 Sep;14(9):831-840. doi: 10.2217/rme-2019-0040. Epub 2019 Aug 29.

Treatment of symptomatic degenerative intervertebral discs with autologous platelet-rich plasma: follow-up at 5-9 years.

Author information

1
Department of Physiatry, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.
2
Department of Physiatry, Hospital for Special Surgery, 535 East 70 Street, New York, NY 10021, USA.
3
Healthcare Research Institute, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA.

Abstract

Aim: This study assessed pain and function at 5-9 years postinjection in a subset of patients who received intradiscal platelet-rich plasma (PRP) injections for moderate-to-severe lumbar discogenic pain. Patients & methods: All patients received injections of intradiscal PRP in a previous randomized controlled trial. Data on pain, function, satisfaction, and need for surgery were collected at one time point of 5-9 years postinjection and compiled with existing data. Results: In comparison to baseline, there were statistically significant improvements in pain and function (p < 0.001). All improvements were clinically significant. Six patients had undergone surgery during the follow-up period. Conclusion: This subset of patients demonstrated statistically and clinically significant improvements in pain and function at 5-9 years postinjection.

KEYWORDS:

autologous PRP; degenerative disc disease; intervertebral disc degeneration; long-term outcomes

PMID:
31464577
PMCID:
PMC6770415
[Available on 2020-09-01]
DOI:
10.2217/rme-2019-0040

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