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Open Access Maced J Med Sci. 2019 Jul 14;7(13):2146-2149. doi: 10.3889/oamjms.2019.584. eCollection 2019 Jul 15.

Concealing Clothing Leading to Severe Vitamin D Deficiency, Osteomalacia and Muscle Weakness.

Author information

1
Clinic of Endocrinology, University Clinical Centre of Kosovo, Prishtina, Kosovo.
2
Medical Faculty, University of Prishtina, Prishtina, Kosovo.

Abstract

BACKGROUND:

Vitamin D deficiency is the most common nutritional deficiency worldwide in all ages. Prolonged and severe vitamin D deficiency can result in secondary hyperparathyroidism and osteomalacia. Vitamin D deficiency can be caused by various factors included here institutionalisation, malabsorption, inadequate exposure to sunlight etc. Osteomalacia is a disorder of decreased mineralisation of newly formed osteoid at sited of bone turnover, which can be manifested with symptoms such as diffuse body aches and pain. Muscles weakness from vitamin D deficiency causes difficulty in walking, developing proximal myopathy. Nearly 30-50% of all age groups are Vitamin D deficient worldwide.

CASE PRESENTATION:

We report a case of 51-years-old woman, with a religious garment, with slowly progressing weakness of the proximal limb muscles, extreme fatigue, chest and lower spine pain, paresthesia, depression, difficulties in walking and waddling gait. On whole-body bone scintigraphy diffuse metabolic changes were present, and in DXA osteoporosis was shown due to severe vitamin D deficiency and secondary hyperparathyroidism. Treatment with high doses of vitamin D and calcium replacement improved clinical manifestation of osteomalacia for few months. Absent of waddling gait with no pain was evident due to the better muscle and bone performance after the treatment.

CONCLUSION:

Suspicious cases for osteomalacia in population wearing a religious garment and those that are not adequately exposed to the sunlight, laboratory evaluation should include measurement of 25 (OH) vitamin D, PTH, calcium, alkaline phosphatase and performing of DXA in order such cases do not get undiagnosed.

KEYWORDS:

Myopathy; Osteomalacia; Vitamin D deficiency

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