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AIDS Behav. 2019 Aug 21. doi: 10.1007/s10461-019-02638-x. [Epub ahead of print]

Differentiating Types of Self-Reported Alcohol Abstinence.

Author information

1
VA Connecticut Healthcare System, 11ACSL-G, 950 Campbell Avenue, West Haven, CT, 06516, USA. kirsha.gordon2@va.gov.
2
Yale University School of Medicine, New Haven, CT, 06510, USA. kirsha.gordon2@va.gov.
3
VA Connecticut Healthcare System, 11ACSL-G, 950 Campbell Avenue, West Haven, CT, 06516, USA.
4
Yale University School of Medicine, New Haven, CT, 06510, USA.
5
Epidemiology & Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK.
6
University of Louisville School of Nursing, Louisville, KY, 42408, USA.
7
Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
8
Corporal Michael J. Crescenz Veterans Affairs Medical Center VISN4 MIRECC, Philadelphia, PA, 19104, USA.
9
Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.
10
National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD, 20892, USA.

Abstract

We contrast three types of abstinence: quit after alcohol associated problems (Q-AP), quit for other reasons (Q-OR), and lifetime abstainer (LTA). We summarized the characteristics of people living with HIV (PLWH), and matched uninfected individuals, by levels of alcohol use and types of abstinence. We then identified factors that differentiate abstinence and determined whether the association with an alcohol biomarker or a genetic polymorphism is improved by differentiating abstinence. Among abstainers, 34% of PLWH and 38% of uninfected were Q-AP; 53% and 53% were Q-OR; and 12% and 10% were LTA. Logistic regression models found smoking, alcohol, cocaine, and hepatitis C increased odds of Q-AP, whereas smoking and marijuana decreased odds of LTA. Differentiating types of abstinence improved association. Q-APs and LTAs can be readily differentiated by an alcohol biomarker and genetic polymorphism. Differentiating type of abstinence may enhance understanding of alcohol health effects.

KEYWORDS:

ADH1B; Alcohol use disorder; HIV; Phosphatidylethanol; Veterans

PMID:
31435887
DOI:
10.1007/s10461-019-02638-x

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