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Int Forum Allergy Rhinol. 2019 Oct;9(10):1144-1150. doi: 10.1002/alr.22392. Epub 2019 Aug 20.

A brief version of the questionnaire of olfactory disorders in patients with chronic rhinosinusitis.

Author information

1
Division of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, University of Virginia, Charlottesville, VA.
2
University of Virginia School of Medicine, Charlottesville, VA.
3
Division of Rhinology and Sinus Surgery, Department of Otolaryngology-Head and Neck Surgery, The Medical University of South Carolina, Charleston, SC.
4
Department of Surgery, Ralph H. Johnson VA Medical Center, Charleston, SC.
5
Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
6
Department of Otolaryngology-Head and Neck Surgery, Oregon Health & Science University, Portland, OR.

Abstract

BACKGROUND:

The Questionnaire of Olfactory Disorders-Negative Statements (QOD-NS) is a valuable instrument in the measurement of olfactory-specific quality of life (QOL). In the clinical setting, patients can be overwhelmed with the time required to complete questionnaires. Our objective was to develop a brief version of the QOD-NS to streamline clinical care and research.

METHODS:

QOD-NS scores from 221 subjects were used to determine which subset of the 17 QOD-NS questions best correlated with total and subdomain QOD-NS scores. An initial pool of 11 questions was made by removing items with ρ < 0.80 to their respective subdomain scores. Next, 500 bootstrapped samples were taken. On each sampe, an all-subsets regression was performed with total QOD-NS scores and QOD-NS subdomain scores as the outcomes. From this, our "top" and "bottom" 10 subsets were identified based on mean r2 value, representation in bootstrap analysis, and number of items.

RESULTS:

All of our top subsets had excellent correlation with total and subdomain QOD-NS scores (mean r2 > 0.90). Our top choice has 7 total questions, is representative of all subdomains, has a mean r2 = 0.92, and was represented in 323 of our 500 bootstrapped samples. The worst-performing subset has 5 items, mean r2 = 0.81, and was represented in only 1 bootstrapped sample.

CONCLUSIONS:

Using less than half of the questions in the QOD-NS, excellent correlations with both total and domain-specific scores are achieved. A brief version of the QOD-NS may prove useful in future clinical and research settings.

KEYWORDS:

olfaction; quality of life; questionnaire of olfactory disorders; sinusitis; smell

PMID:
31430061
PMCID:
PMC6773507
[Available on 2020-10-01]
DOI:
10.1002/alr.22392

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