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Indian J Med Microbiol. 2019 Jan-Mar;37(1):120-122. doi: 10.4103/ijmm.IJMM_18_371.

Primary amoebic meningoencephalitis in an infant.

Author information

1
Department of Microbiology, QRG Central Hospital and Research Centre, Faridabad, Haryana, India.
2
Department of Pediatrics, QRG Health City, Faridabad, Haryana, India.
3
Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Abstract

Primary amoebic meningoencephalitis is rare but fatal disease encountered in immunocompetent individuals. Here, we present a case of a previously healthy 8-month-old female child, who presented with features of meningoencephalitis of 2 days' duration. Rapidly moving trophozoites of amoeba were observed in cerebrospinal fluid, which were confirmed to be Naegleria fowleri on polymerase chain reaction. Broad-spectrum antimicrobial therapy with ceftriaxone, vancomycin, amphotericin B and acyclovir was initiated. However, the patient deteriorated and left the hospital against medical advice. The isolation of N. fowleri in this case demands for increased awareness for prompt diagnosis and management in view of its high mortality.

KEYWORDS:

Mortality; Naegleria fowleri; parasite; primary amoebic meningoencephalitis

PMID:
31424023
DOI:
10.4103/ijmm.IJMM_18_371
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