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Indian J Med Microbiol. 2019 Jan-Mar;37(1):95-98. doi: 10.4103/ijmm.IJMM_18_248.

Relative potency of different generic brands of meropenem, colistin and fosfomycin: Implications for antimicrobial therapy and antimicrobial formulary.

Author information

1
Department of Microbiology, Tata Medical Center, Kolkata, West Bengal, India.
2
Department of Clinical Hematology, Tata Medical Center, Kolkata, West Bengal, India.

Abstract

There is a need of a relatively simple and inexpensive method for the determination of relative potency of various generic brands of antibiotics in comparison to original products. The current study describes an agar diffusion method which can be performed in any microbiology laboratory, is cheap (costs $2 per test) and its results can be available after overnight incubation. The results show that neither all generics are reliable nor are all generic antibiotics of poor quality.

KEYWORDS:

Agar diffusion; colistin; fosfomycin; generic brands; meropenem; relative potency

PMID:
31424016
DOI:
10.4103/ijmm.IJMM_18_248
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