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Nat Genet. 2019 Sep;51(9):1423-1424. doi: 10.1038/s41588-019-0495-7.

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Kunkle BW1, Grenier-Boley B2,3,4, Sims R5,6, Bis JC7, Damotte V2,3,4, Naj AC8, Boland A9, Vronskaya M5, van der Lee SJ10, Amlie-Wolf A11, Bellenguez C2,3,4, Frizatti A5, Chouraki V2,3,4,12,13, Martin ER14, Sleegers K15,16, Badarinarayan N5, Jakobsdottir J17, Hamilton-Nelson KL14, Moreno-Grau S18,19, Olaso R9, Raybould R5,6, Chen Y20, Kuzma AB11, Hiltunen M21,22, Morgan T5, Ahmad S10, Vardarajan BN23,24,25, Epelbaum J26, Hoffmann P27,28,29, Boada M18,19, Beecham GW14, Garnier JG9, Harold D30, Fitzpatrick AL31,32, Valladares O11, Moutet ML9, Gerrish A33, Smith AV34,35, Qu L11, Bacq D9, Denning N5,6, Jian X36, Zhao Y11, Del Zompo M37, Fox NC33,38, Choi SH18, Mateo I39, Hughes JT40, Adams HH10, Malamon J11, Sanchez-Garcia F41, Patel Y40, Brody JA7, Dombroski BA11, Naranjo MCD41, Daniilidou M42, Eiriksdottir G17, Mukherjee S43, Wallon D44, Uphill J45, Aspelund T17,46, Cantwell LB11, Garzia F9, Galimberti D47,48, Hofer E49,50, Butkiewicz M51, Fin B9, Scarpini E47,48, Sarnowski C20, Bush WS51, Meslage S9, Kornhuber J52, White CC53, Song Y51, Barber RC54, Engelborghs S55,56, Sordon S57, Voijnovic D10, Adams PM58, Vandenberghe R59, Mayhaus M57, Cupples LA12,20, Albert MS60, De Deyn PP55,56, Gu W57, Himali JJ12,13,20, Beekly D61, Squassina A37, Hartmann AM62, Orellana A18, Blacker D63,64, Rodriguez-Rodriguez E39, Lovestone S65, Garcia ME66, Doody RS67, Munoz-Fernadez C41, Sussams R68, Lin H69, Fairchild TJ70, Benito YA41, Holmes C68, Karamujić-Čomić H10, Frosch MP71, Thonberg H72,73, Maier W74,75, Roshchupkin G10, Ghetti B76, Giedraitis V77, Kawalia A78, Li S20, Huebinger RM79, Kilander L77, Moebus S80, Hernández I18,19, Kamboh MI81,82,83, Brundin R77, Turton J84, Yang Q20, Katz MJ85, Concari L86,87, Lord J84, Beiser AS12,13,20, Keene CD88, Helisalmi S21,22, Kloszewska I89, Kukull WA32, Koivisto AM21,22, Lynch A90,91, Tarraga L18,19, Larson EB92, Haapasalo A93, Lawlor B90,91, Mosley TH94, Lipton RB85, Solfrizzi V95, Gill M90,91, Longstreth WT Jr32,96, Montine TJ88, 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Becker JT81,158,159, Passmore P133, Bigio EH160,161, Schott JM33, Bird TD96,127, Warren JD33, Boeve BF102, Lupton MK40,162, Bowen JD163, Proitsi P40, Boxer A164, Powell JF40, Burke JR165, Kauwe JSK166, Burns JM167, Mancuso M168, Buxbaum JD118,169,170, Bonuccelli U168, Cairns NJ171, McQuillin A172, Cao C173, Livingston G172, Carlson CS145,146, Bass NJ172, Carlsson CM174, Hardy J175, Carney RM176, Bras J38,177, Carrasquillo MM178, Guerreiro R38,177, Allen M178, Chui HC179, Fisher E177, Masullo C180, Crocco EA181, DeCarli C182, Bisceglio G178, Dick M183, Ma L178, Duara R184, Graff-Radford NR178, Evans DA185, Hodges A186, Faber KM139, Scherer M187, Fallon KB188, Riemenschneider M57, Fardo DW189, Heun R75, Farlow MR141, Kölsch H75, Ferris S190, Leber M191, Foroud TM139, Heuser I192, Galasko DR193, Giegling I62, Gearing M194,195, Hüll M196, Geschwind DH197, Gilbert JR14, Morris J198,199, Green RC200, Mayo K198,201,202, Growdon JH203, Feulner T57, Hamilton RL204, Harrell LE205, Drichel D206, 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Author information

1
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. bkunkle@miami.edu.
2
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.
3
Institut Pasteur de Lille, Lille, France.
4
Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.
5
Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.
6
UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK.
7
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.
8
Department of Biostatistics and Epidemiology/Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
9
Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France.
10
Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.
11
Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
12
Framingham Heart Study, Framingham, MA, USA.
13
Department of Neurology, Boston University School of Medicine, Boston, MA, USA.
14
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.
15
Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.
16
Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
17
Icelandic Heart Association, Kopavogur, Iceland.
18
Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.
19
Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain.
20
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
21
Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
22
Department of Neurology, Kuopio University Hospital, Kuopio, Finland.
23
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.
24
Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.
25
Department of Neurology, Columbia University, New York, NY, USA.
26
UMR 894, Center for Psychiatry and Neuroscience, Inserm, Université Paris Descartes, Paris, France.
27
Institute of Human Genetics, University of Bonn, Bonn, Germany.
28
Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.
29
Division of Medical Genetics, University Hospital and Department of Biomedicine, University of Basel, Basel, Switzerland.
30
School of Biotechnology, Dublin City University, Dublin, Ireland.
31
Department of Family Medicine, University of Washington, Seattle, WA, USA.
32
Department of Epidemiology, University of Washington, Seattle, WA, USA.
33
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
34
Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
35
Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
36
Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA.
37
Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.
38
UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
39
Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain.
40
Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
41
Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain.
42
Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
43
Department of Medicine, University of Washington, Seattle, WA, USA.
44
Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France.
45
Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK.
46
Centre for Public Health, University of Iceland, Reykjavik, Iceland.
47
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.
48
University of Milan, Centro Dino Ferrari, Milan, Italy.
49
Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.
50
Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria.
51
Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA.
52
Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany.
53
Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
54
Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA.
55
Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.
56
Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium.
57
Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany.
58
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.
59
Laboratory for Cognitive Neurology, Department of Neurology, University Hospital and University of Leuven, Leuven, Belgium.
60
Department of Neurology, Johns Hopkins University, Baltimore, MD, USA.
61
National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA.
62
Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany.
63
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.
64
Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
65
Department of Psychiatry, University of Oxford, Oxford, UK.
66
Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA.
67
Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine, Houston, TX, USA.
68
Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK.
69
Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA.
70
Office of Strategy and Measurement, University of North Texas Health Science Center, Fort Worth, TX, USA.
71
C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown, MA, USA.
72
Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.
73
Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Alzheimer Research Center, Division of Neurogeriatrics, Solna, Sweden.
74
German Center for Neurodegenerative Diseases, Bonn, Germany.
75
Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
76
Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA.
77
Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden.
78
Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.
79
Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
80
Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany.
81
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.
82
Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.
83
Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.
84
Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
85
Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
86
Section of Neuroscience, DIMEC-University of Parma, Parma, Italy.
87
FERB-Alzheimer Center, Gazzaniga (Bergamo), Italy.
88
Department of Pathology, University of Washington, Seattle, WA, USA.
89
Elderly and Psychiatric Disorders Department, Medical University of Lodz, Lodz, Poland.
90
Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.
91
St. James's Hospital and Trinity College, Dublin, Ireland.
92
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.
93
A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
94
Departments of Medicine, Geriatrics, Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS, USA.
95
Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unity, University of Bari, Bari, Italy.
96
Department of Neurology, University of Washington, Seattle, WA, USA.
97
Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy.
98
Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.
99
Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain.
100
Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.
101
Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands.
102
Department of Neurology, Mayo Clinic, Rochester, MN, USA.
103
CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France.
104
Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy.
105
School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.
106
Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.
107
Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.
108
Arizona Alzheimer's Consortium, Phoenix, AZ, USA.
109
Banner Alzheimer's Institute, Phoenix, AZ, USA.
110
Department of Psychiatry, University of Arizona, Phoenix, AZ, USA.
111
Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.
112
Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA.
113
University Paris Descartes, EA 4468, AP-HP, Geriatrics Department, Hôpital Broca, Paris, France.
114
Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy.
115
Departments of Psychiatry, Medicine, Family & Community Medicine, South Texas Veterans Health Administration Geriatric Research Education & Clinical Center (GRECC), UT Health Science Center at San Antonio, San Antonio, TX, USA.
116
University of Bordeaux, Inserm 1219, Bordeaux, France.
117
Department of Neurology, Bordeaux University Hospital / CHU de Bordeaux, Bordeaux, France.
118
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
119
Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.
120
AP-HP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France.
121
Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy.
122
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
123
Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada.
124
Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.
125
Montpellier University, Montpellier, France.
126
Department of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.
127
VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA.
128
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
129
Institut de la Mémoire et de la Maladie d'Alzheimer and Institut du Cerveau et de la Moelle Épinière, Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France.
130
Institut des Neurosciences Translationnelles de Paris, Institut du Cerveau et de la Moelle Épinière, Paris, France.
131
Inserm, CNRS, UMR-S975, Institut du Cerveau et de la Moelle Epinière, Paris, France.
132
Sorbonne Universités, Université Pierre et Marie Curie, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France.
133
Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
134
Departments of Neurology, Pharmacology & Neuroscience, Texas Tech University Health Science Center, Lubbock, TX, USA.
135
Department of Neurology, University of Michigan, Ann Arbor, MI, USA.
136
Geriatric Research, Education and Clinical Center (GRECC), VA Ann Arbor Healthcare System (VAAAHS), Ann Arbor, MI, USA.
137
Michigan Alzheimer Disease Center, Ann Arbor, MI, USA.
138
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
139
Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.
140
Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.
141
Department of Neurology, Indiana University, Indianapolis, IN, USA.
142
Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA.
143
Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
144
Geriatric Research, Education and Clinical Center (GRECC), University of Wisconsin, Madison, WI, USA.
145
Department of Medicine, University of Wisconsin, Madison, WI, USA.
146
Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA.
147
AXA Research Fund & Sorbonne University Chair, Paris, France.
148
Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France.
149
Brain & Spine Institute, Inserm U 1127, CNRS UMR 7225, Paris, France.
150
Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.
151
Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain.
152
UK Dementia Research Institute, University of Cambridge, Cambridge, UK.
153
Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
154
Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.
155
Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA.
156
Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.
157
Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Phoenix, AZ, USA.
158
Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.
159
Department of Psychology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
160
Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
161
Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
162
Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia.
163
Swedish Medical Center, Seattle, WA, USA.
164
Department of Neurology, University of California, San Francisco, San Francisco, CA, USA.
165
Department of Neurology, Duke University, Durham, NC, USA.
166
Departments of Biology, Brigham Young University, Provo, UT, USA.
167
University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA.
168
Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy.
169
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
170
Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
171
Department of Pathology and Immunology, Washington University, St. Louis, MO, USA.
172
Division of Psychiatry, University College London, London, UK.
173
USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA.
174
Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
175
Department of Molecular Neuroscience, UCL, Institute of Neurology, London, UK.
176
Mental Health & Behavioral Science Service, Bruce W. Carter VA Medical Center, Miami, FL, USA.
177
Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.
178
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.
179
Department of Neurology, University of Southern California, Los Angeles, CA, USA.
180
Department of Neurology, Catholic University of Rome, Rome, Italy.
181
Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA.
182
Department of Neurology, University of California, Davis, Sacramento, CA, USA.
183
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA.
184
Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, FL, USA.
185
Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA.
186
Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
187
Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.
188
Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
189
Sanders-Brown Center on Aging, Department of Biostatistics, University of Kentucky, Lexington, KY, USA.
190
Department of Psychiatry, New York University, New York, NY, USA.
191
Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
192
Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany.
193
Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.
194
Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.
195
Emory Alzheimer's Disease Center, Emory University, Atlanta, GA, USA.
196
Department of Psychiatry, University of Freiburg, Freiburg, Germany.
197
Neurogenetics Program, University of California, Los Angeles, Los Angeles, CA, USA.
198
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
199
Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA.
200
Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
201
Department of Neurology, Washington University, St. Louis, MO, USA.
202
Department of Genetics, Washington University, St. Louis, MO, USA.
203
Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA.
204
Department of Pathology (Neuropathology), University of Pittsburgh, Pittsburgh, PA, USA.
205
Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA.
206
Cologne Center for Genomics, University of Cologne, Cologne, Germany.
207
Department of Pathology, Duke University, Durham, NC, USA.
208
Department of Genome Sciences, University of Washington, Seattle, WA, USA.
209
Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA.
210
Sanders-Brown Center on Aging, College of Public Health, Department of Epidemiology, University of Kentucky, Lexington, KY, USA.
211
Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain.
212
Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.
213
Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland.
214
Department of Neurology, Oregon Health &Science University, Portland, OR, USA.
215
Department of Neurology, Portland Veterans Affairs Medical Center, Portland, OR, USA.
216
Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA.
217
Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA.
218
Inserm U558, University of Toulouse, Toulouse, France.
219
Department of Neuropsychology, University of California San Francisco, San Francisco, CA, USA.
220
Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK.
221
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA.
222
Department of Neurology, Emory University, Atlanta, GA, USA.
223
Institute for Stroke and Dementia Research, Klinikum der Universität München, Munich, Germany.
224
German Center for Neurodegenerative Diseases, Munich, Germany.
225
Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA.
226
Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
227
Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
228
Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Munich, Germany.
229
Helmholtz Center Munich, Institute of Epidemiology, Neuherberg, Munich, Germany.
230
Ludwig-Maximilians University Chair of Epidemiology, Munich, Germany.
231
Joint Biobank Munich and KORA Biobank, Baltimore, MD, USA.
232
Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA.
233
Human Genetics, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, UK.
234
Department of Medicine-Pulmonary, New York University, New York, NY, USA.
235
Department of Neurology, University of Miami, Miami, FL, USA.
236
Department of Pathology, University of California, San Diego, La Jolla, CA, USA.
237
Institute of Neurology, Catholic University of Sacred Hearth, Rome, Italy.
238
School of Nursing Northwest Research Group on Aging, University of Washington, Seattle, WA, USA.
239
Institute of Primary Care and Public Health, Cardiff University, University Hospital of Wales, Cardiff, UK.
240
Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
241
Cambridge Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK.
242
Weill Institute for Neurosciences, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.
243
Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany.
244
Department of Pathology, University of Southern California, Los Angeles, CA, USA.
245
Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA.
246
Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK.
247
UK Dementia Research Institute, King's College London, London, UK.
248
Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, Goettingen, Germany.
249
German Center for Neurodegenerative Diseases, Goettingen, Germany.
250
IBiMED, Medical Sciences Department, University of Aveiro, Aveiro, Portugal.
251
Molecular Genetics Laboratory-Hospital, University of Central Asturias, Oviedo, Spain.
252
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
253
Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA.
254
Department of Neurology, University of California, Irvine, Irvine, CA, USA.
255
Department of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, Florence, Italy.
256
Centro di Ricerca, Trasferimento e Alta Formazione DENOTHE, University of Florence, Florence, Italy.
257
Department of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.
258
IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
259
Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.
260
Division of Neuropsychiatry, Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA.
261
Alzheimer's Disease Center, New York University, New York, NY, USA.
262
Oxford Healthy Aging Project, Clinical Trial Service Unit, University of Oxford, Oxford, UK.
263
Department of Epidemiology, Columbia University, New York, NY, USA.
264
Oxford Project to Investigate Memory and Ageing, University of Oxford, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK.
265
Department of Neurology, Keck School of Medicine at the University of Southern California, Los Angeles, Los Angeles, CA, USA.
266
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
267
Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
268
Department of Pathology (Neuropathology), Rush University Medical Center, Chicago, IL, USA.
269
Department of Psychiatry, University of Southern California, Los Angeles, CA, USA.
270
Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
271
Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
272
Sanders-Brown Center on Aging, Department of Neuroscience, University of Kentucky, Lexington, KY, USA.
273
Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA.
274
Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
275
Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Pathology, Columbia University, New York, NY, USA.
276
Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
277
Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA.
278
Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
279
Department of Human Genetics, Emory University, Atlanta, GA, USA.
280
Department of Pathology, Oregon Health & Science University, Portland, OR, USA.
281
National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.
282
Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Division of Molecular Biology and Biochemistry, Medical University Graz, Graz, Austria.
283
Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
284
Department Geriatric Care, Orthogeriatrics and Rehabilitation, Galliera Hospital, Genova, Italy.
285
IdiPAZ, Instituto de Investigación Sanitaria la Paz, Madrid, Spain.
286
Centro de Biologia Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain.
287
German Center for Neurodegenerative Diseases, Berlin, Germany.
288
Instituto di Ricovero e Cura a Carattere Scientifico, Associazione Oasi Maria Santissima Srl, Troina, Italy.
289
Center for Translational and Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY, USA.
290
Memory Unit, Neurology Department and Sant Pau Biomedical Research Institute, Hospital de la Santa Creu i Sant Pau, Autonomous University Barcelona, Barcelona, Spain.
291
Somerset Partnership NHS Trust, Somerset, UK.
292
The Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
293
Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
294
University of Bristol Medical School, Learning & Research level 2, Southmead Hospital, Bristol, UK.
295
Department of Neurology, Mayo Clinic, Jacksonville, FL, USA.
296
Memory Research and Resources Center, CMRR de Bordeaux, Bordeaux, France.
297
Utah State University, Logan, UT, USA.
298
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
299
Departments of Radiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
300
Department of Research Rouvray Psychiatric Hospital, Sotteville-lès-Rouen, France.
301
Department of Neurology, Medical University Graz, Graz, Austria.
302
Center for Applied Genomics, Children's Hospital of Philadelphia, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
303
Division of Human Genetics, Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
304
Department of Ophthalmology, Boston University School of Medicine, Boston University, Boston, MA, USA.
305
Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA.
306
Department of Health Services, University of Washington, Seattle, WA, USA.
307
Kaiser Permanente, Washington Health Research Institute, Seattle, WA, USA.
308
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA.
309
Centre Hospitalier Universitaire de Lille, Lille, France.
310
Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France. jean-charles.lambert@pasteur-lille.fr.
311
Institut Pasteur de Lille, Lille, France. jean-charles.lambert@pasteur-lille.fr.
312
Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France. jean-charles.lambert@pasteur-lille.fr.
313
John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. mpericak@miami.edu.

Abstract

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

PMID:
31417202
DOI:
10.1038/s41588-019-0495-7

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