Correction: Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner

Saiprasad Gowrikumar; Rizwan Ahmad; Srijayaprakash Babu Uppada; Mary K Washington; Chanjuan Shi; Amar B Singh; Punita Dhawan

doi:10.1038/s41388-019-0864-9

Correction: Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner

Oncogene. 2019 Sep;38(38):6566. doi: 10.1038/s41388-019-0864-9.

Authors

Saiprasad Gowrikumar¹, Rizwan Ahmad¹, Srijayaprakash Babu Uppada¹, Mary K Washington², Chanjuan Shi², Amar B Singh^{1

3

4}, Punita Dhawan^{5

6

7}

Affiliations

¹ Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.
² Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA.
³ VA Nebraska-Western Iowa Health Care System, Omaha, NE, USA.
⁴ Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.
⁵ Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA. punita.dhawan@unmc.edu.
⁶ VA Nebraska-Western Iowa Health Care System, Omaha, NE, USA. punita.dhawan@unmc.edu.
⁷ Buffet Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA. punita.dhawan@unmc.edu.

PMID: 31417178
DOI: 10.1038/s41388-019-0864-9

Abstract

In Fig. 1 legend, should read as follows: Cld-1 intensifies colitis, leads to impaired recovery from DSS induction and triggers dysplasia: a Schematic illustration of the experimental protocol. Age-matched and sex-matched WT (n = 8) and Cld-1 Tg (n = 8) mice were treated with 2.5% DSS in drinking water for 7 days ad libitum (colitis group), followed by drinking water for 10 days (DSS recovery group). b Representative histological images of WT and Cld-1 Tg mice under DSS and DSS recovery protocol showing regenerative crypts in WT DSS Recovery and dysplastic crypts in Cld-1 Tg Recovery. c The mean changes in body weight of the WT and Cld-1 Tg mice after being fed with 2.5% DSS were measured every day until day 7 for the colitis group and day 10 for the DSS recovery group. The percentage of mice possessing dysplastic crypt in the recovery protocol among WT and Cld-1 Tg groups. Results are statistically significant at p < 0.05. Values sharing following symbols differ significantly, asterisk (*) compared with WT DSS Recovery.

Publication types

Published Erratum