Format

Send to

Choose Destination
Neurogastroenterol Motil. 2019 Aug 12:e13679. doi: 10.1111/nmo.13679. [Epub ahead of print]

The international anorectal physiology working group (IAPWG) recommendations: Standardized testing protocol and the London classification for disorders of anorectal function.

Author information

1
Queen Mary, University of London, London, UK.
2
University of Zürich, Zürich, Switzerland.
3
Medical College of Georgia, Augusta, Georgia, USA.
4
University Aldo Moro of Bari, Bari, Italy.
5
Mayo Clinic, Rochester, Minnesota, USA.
6
Monash University and Alfred Health, Melbourne, Victoria, Australia.
7
Michigan Medicine, Ann Arbor, Michigan, USA.
8
AOUI Verona, Verona, Italy.
9
Flinders University, Adelaide, South Australia, Australia.
10
University College London, London, UK.
11
National University Hospital Singapore, Singapore City, Singapore.
12
UMC Amsterdam, Amsterdam, The Netherlands.
13
Asan Medical Center, Seoul, Korea.
14
Harvard Medical School, St, Boston, Massachusetts, USA.
15
University of Sydney and Royal North Shore Hospital, Sydney, New South Wales, Australia.
16
University of California, Berkeley, California, USA.
17
Université de Lyon et Hospices Civils de Lyon, Lyon, France.
18
University College Dublin, Dublin, Ireland.
19
Krankenhaus Vilsbiburg and Technical University Munich, Munich, Germany.
20
University of Veracruz, Veracruz, Mexico.
21
University of Colorado, Denver, Colorado, USA.
22
St Mark's Hospital and Imperial College London, London, UK.
23
AP-HM - Aix-Marseille University, Marseille, France.
24
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Abstract

BACKGROUND:

This manuscript summarizes consensus reached by the International Anorectal Physiology Working Group (IAPWG) for the performance, terminology used, and interpretation of anorectal function testing including anorectal manometry (focused on high-resolution manometry), the rectal sensory test, and the balloon expulsion test. Based on these measurements, a classification system for disorders of anorectal function is proposed.

METHODS:

Twenty-nine working group members (clinicians/academics in the field of gastroenterology, coloproctology, and gastrointestinal physiology) were invited to six face-to-face and three remote meetings to derive consensus between 2014 and 2018.

KEY RECOMMENDATIONS:

The IAPWG protocol for the performance of anorectal function testing recommends a standardized sequence of maneuvers to test rectoanal reflexes, anal tone and contractility, rectoanal coordination, and rectal sensation. Major findings not seen in healthy controls defined by the classification are as follows: rectoanal areflexia, anal hypotension and hypocontractility, rectal hyposensitivity, and hypersensitivity. Minor and inconclusive findings that can be present in health and require additional information prior to diagnosis include anal hypertension and dyssynergia.

CONCLUSIONS AND INFERENCES:

This framework introduces the IAPWG protocol and the London classification for disorders of anorectal function based on objective physiological measurement. The use of a common language to describe results of diagnostic tests, standard operating procedures, and a consensus classification system is designed to bring much-needed standardization to these techniques.

KEYWORDS:

anorectal function testing; anorectal manometry; balloon expulsion test; functional anorectal disorders; rectal sensory test

PMID:
31407463
DOI:
10.1111/nmo.13679

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center