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J Exp Med. 2019 Sep 2;216(9):1972-1973. doi: 10.1084/jem.20191098. Epub 2019 Aug 12.

ILC2s chew the fat.

Author information

1
Department of Dermatology, University of California, San Francisco, San Francisco, CA.
2
Department of Medicine, University of California, San Francisco, San Francisco, CA richard.locksley@ucsf.edu.
3
Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, CA.
4
Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA.

Abstract

In this issue of JEM, Rana et al. (https://doi.org/10.1084/jem.20190689) report that adipose tissue multipotent stromal cells (MSCs) provide multifaceted support for adipose tissue-resident ILC2s through contact-mediated proliferation and IL-33-mediated stress-induced activation.

PMID:
31405894
DOI:
10.1084/jem.20191098

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