Format

Send to

Choose Destination
Diabetes Metab Syndr. 2019 Jul - Aug;13(4):2803-2811. doi: 10.1016/j.dsx.2019.07.041. Epub 2019 Jul 24.

Health risks and interventions in prediabetes: A review.

Author information

1
Department of Biochemistry, Gajra Raja Medical College, Jiwaji University, Gwalior, Madhya Pradesh, 474009, India; Department of Biochemistry, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh, 251203, India. Electronic address: mahatroshan79@gmail.com.
2
University of Kota, Kota, Rajasthan, 324005, India.
3
Department of Biochemistry, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh, 251203, India.
4
Department of Biochemistry, Shyam Shah Medical College, Rewa, Madhya Pradesh, 486001, India.

Abstract

Prediabetes is a condition which appears prior to the development of diabetes in which blood glucose is abnormally high but do not reach the diagnostic threshold of type 2 diabetes mellitus. It is characterized by a cluster of metabolic abnormalities viz. dysglycemia, dyslipidemia, hypertension, physical inactivity, obesity, insulin resistance, procoagulant state, endothelial dysfunction, oxidative stress and inflammation, placing prediabetic subjects to an increased risk for diabetes and its complications. Recent studies demonstrate that complications of diabetes i.e. microvascular and macrovascular complications may manifest in some prediabetic subjects. This article reviews prediabetes-related risk factors and health issues. In addition, this article also highlights the interventions to prevent the development of diabetes in prediabetic subjects.

KEYWORDS:

Complications; Interventions; Prediabetes; Risk factors

PMID:
31405710
DOI:
10.1016/j.dsx.2019.07.041

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center