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Cureus. 2019 Jun 3;11(6):e4815. doi: 10.7759/cureus.4815.

Colonic Perineurioma's Malignant Proximity to Serrated Colonic Polyps.

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Internal Medicine, The Brooklyn Hospital Center, Affiliate of the Mount Sinai Hospital, Brooklyn, USA.
Gastroenterology, Pali Momi Medical Center, Honolulu, USA.


A colonic perineurioma is often considered a benign cousin to a colonic polyp. However, in the submucosal type of perineurioma, it is important to rule out the malignant gastrointestinal stromal tumor (GIST). Alternatively, in the BRAF-positive serrated types of perineuriomas, surveillance is equivalent to intervals designated to serrated polyps due to a similar malignant potential. These versions serve as reminders that colonic perineuriomas are not to be disregarded.


braf; colon polyp; colonic polyp; gist; perineurioma; serrated polyp

Conflict of interest statement

The authors have declared that no competing interests exist.

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