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Perspect Clin Res. 2019 Jul-Sep;10(3):125-129. doi: 10.4103/picr.PICR_99_18.

Quality of life among HIV-tuberculosis co-infected patients.

Author information

1
Department of Medicine, Patliputra Medical College and Hospital, Dhanbad, Jharkhand, India.
2
Department of Obstetrics and Gynecology, Medical College, Kolkata, West Bengal, India.
3
Department of Medicine, Assam Medical College, Dibrugarh, Assam, India.
4
Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.
5
Department of Preventive and Social Medicine, Kasturba Medical College, Mangalore, Karnataka, India.

Abstract

Background:

India is the world's third leading country in terms of people living with human deficiency virus (HIV) (2.1 million) with 0.4 million deaths due to HIV-associated tuberculosis (TB). Physical and mental stress degrades the quality of life (QOL) in these patients. Studies have been done in HIV patients but very few on HIV-TB co-infected patients. Our study aims at assessing and comparing the QOL in HIV patients with and without TB.

Materials and Methods:

It was a cross-sectional study done at Antiretroviral Treatment Center of KMC, Mangalore and District Wenlock Hospital, Mangalore, over 6 months. A sample size was 104. Semi-structured questionnaire to collect clinico-demographic data, World Health Organization QOL (WHOQOL)-HIV BREF to assess the QoL, and Beck's Depression Inventory Scale (Physical health, psychological well-being, social relationship, environmental health, level of independence, and spiritual health) to identify depression were used. The Cronbach's alpha was used to measure the internal consistency for each domain of the WHOQOL-HIV instrument.

Results:

HIV-TB co-infected patients had a lower mean score in all domains as compare to only HIV patients, suggesting that HIV-TB co-infected patients had a poor QOL (P < 0.05). Internal consistency of each domain was good (α >0.7).

Conclusion:

To improve the QOL in HIV patients, it is important to identify the determinants of QOL and work toward its improvement.

KEYWORDS:

Beck's Depression Inventory Scale; World Health Organization quality of life-human deficiency virus BREF; human deficiency virus; quality of life

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