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Avicenna J Med. 2019 Jul-Sep;9(3):107-110. doi: 10.4103/ajm.AJM_189_18.

Overprescription of antibiotics in patients with community-acquired pneumonia in the intensive care unit.

Author information

1
Department of Medicine, College of Medicine, University of Arizona, Tucson, AZ, USA.
2
Department of Pharmacy Practice and Science, College of Pharmacy, University of Arizona, Tucson, AZ, USA.
3
Department of Medicine, Baylor College of Medicine, Houston, TX, USA.

Abstract

Purpose:

We aimed to assess factors associated with therapy failure in patients with community-acquired pneumonia in the intensive care unit (ICU).

Methods:

Electronic charts of patients with International Classification of Diseases, Ninth Revision, codes of pneumonia who were admitted to the ICU at a tertiary academic medical center in Southern Arizona were reviewed.

Results:

Antipseudomonal coverage and anti-methicillin-resistant Staphylococcus aureus (MRSA) coverage were often prescribed (58.4% and 54.1%, respectively). Antipseudomonal coverage was rarely necessary as pseudomonal pneumonia was found in only one case (0.9%). Antipseudomonal and anti-MRSA coverage was not associated with improved outcomes.

Conclusion:

Overprescription of antibiotics in this population remains a significant problem. More work is needed to further limit unnecessary antibiotic use.

KEYWORDS:

Antimicrobials; incentive care unit; outcomes; overuse; respiratory infection

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