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Trends Neurosci. 2019 Aug 6. pii: S0166-2236(19)30129-8. doi: 10.1016/j.tins.2019.07.006. [Epub ahead of print]

Éloge de la Fuite: Neural Circuits for Avoiding Dangerous Situations.

Author information

1
Neurobiology Division, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
2
Neurobiology Division, Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK. Electronic address: mtripodi@mrc-lmb.cam.ac.uk.

Abstract

When facing threats, animals not only innately freeze or flee, but can also learn to avoid harmful situations, a behaviour known as 'active avoidance'. A recent study by Hormigo et al. (J. Neurosci., 2019) provides new insights into the neural circuit responsible for this behaviour, placing the pedunculopontine tegmental nucleus (PPT) at its centre.

KEYWORDS:

active avoidance; decision making; motor control

PMID:
31399288
DOI:
10.1016/j.tins.2019.07.006

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