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Cell. 2019 Aug 8;178(4):769-771. doi: 10.1016/j.cell.2019.07.022.

A Light Touch on Sociability.

Author information

1
Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland.
2
Department of Fundamental Neurosciences, University of Lausanne, Lausanne, Switzerland; Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy. Electronic address: claudia.bagni@unil.ch.

Abstract

Autism spectrum disorder (ASD) is prevalent, complex, and heterogeneous, and currently there is no cure. Identifying shared mechanisms across the ASD spectrum is of utmost importance for therapeutic intervention. Orefice et al. show that tackling the GABAA receptor pathway in the peripheral somatosensory system in various ASD mouse models rescues core ASD-like phenotypes.

PMID:
31398332
DOI:
10.1016/j.cell.2019.07.022

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