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J Am Acad Dermatol. 2020 Jan;82(1):240-243. doi: 10.1016/j.jaad.2019.07.097. Epub 2019 Aug 5.

Efficacy and safety of methotrexate versus placebo as add-on therapy to H1 antihistamines for patients with difficult-to-treat chronic spontaneous urticaria: A randomized, controlled trial.

Author information

1
Department of Dermatology, University Hospital of Tours, Tours, France; Clinical Investigation Center, INSERM CIC 1415, University Hospital of Tours, Tours, France; Université de Tours, Université de Nantes, INSERM U1246-SPHERE, France. Electronic address: soleducq@gmail.com.
2
Department of Dermatology, University Hospital of Tours, Tours, France; ISP 1282 INRA, University of Tours, Tours, France.
3
Department of Dermatology, University Hospital Center of Nantes, Nantes, France.
4
Department of Dermatology and Allergology, Hospital Tenon, Paris, Assistance Publique Hopitaux de Paris, Sorbonne Université, Paris, France.
5
CHU Lille, Service de dermatologie et vénérologie, F-59000 Lille, France, Univ. Lille, Inserm U995 - LIRIC - Lille Inflammation Research International Center, F-59000 Lille, France.
6
Department of Dermatology, Assistance Publique Hôpitaux de Paris, Henri-Mondor Hospital, Créteil, France.
7
Department of Dermatology, Hospital Center of le Mans, le Mans, France.
8
Department of Dermatology, Reims University Hospital, University of Reims-Champagne-Ardenne, Reims, France.
9
Department of Dermatology, University Hospital of Poitiers, Poitiers, France.
10
Department of Dermatology, University Hospital of Brest, Brest, France.
11
Department of Dermatology, University Hospital of Rennes, Rennes, France.
12
Department of Dermatology, University Hospital of Montpellier, Montpellier, France.
13
Department of Pharmacy, University Hospital of Tours, Tours, France.
14
Department of Dermatology, University Hospital of Tours, Tours, France.
15
Clinical Investigation Center, INSERM CIC 1415, University Hospital of Tours, Tours, France; Université de Tours, Université de Nantes, INSERM U1246-SPHERE, France.
16
Department of Dermatology, University Hospital of Tours, Tours, France; Université de Tours, Université de Nantes, INSERM U1246-SPHERE, France.
PMID:
31394130
DOI:
10.1016/j.jaad.2019.07.097

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