Format

Send to

Choose Destination
Int J Colorectal Dis. 2019 Aug 7. doi: 10.1007/s00384-019-03359-2. [Epub ahead of print]

Quality of life after end colostomy without mesh and with prophylactic synthetic mesh in sublay position: one-year results of the STOMAMESH trial.

Author information

1
Department of Surgical and Perioperative Sciences, Surgery, Umeå University, SE-901 88, Umeå, Sweden. simon.naverlo@umu.se.
2
Department of Surgical and Perioperative Sciences, Surgery, Umeå University, SE-901 88, Umeå, Sweden.
3
Sunderby Research Unit, Umeå University, Luleå, Sweden.

Abstract

PURPOSE:

To determine whether prophylactic mesh in a sublay position has an impact on the quality-of-life (QoL) of patients receiving an end colostomy.

METHODS:

One-year follow-up of patients from the STOMAMESH trial, a randomized controlled double-blinded multicenter study. Patients were randomized to either prophylactic synthetic mesh with a cruciform incision in the center, placed in sublay position, or no prophylactic mesh. Patients attended a 1-year visit and responded to the questionnaires EORTC QLQ C-30 and CR-38. The impact of having a mesh on QoL was determined by comparing a group of patients receiving a mesh with a group without. A subgroup analysis was made depending on whether a PSH was clinically present or not.

RESULTS:

Of the 232 randomized patients, 211 patients reached the 1-year clinical follow-up. The response rate of these 211 patients was 70%. No differences were seen in global QoL between the groups. Mesh patients reported significantly less stoma-related problems (p = 0.014) but more sexual problems in males (p = 0.022). When excluding patients with a clinical diagnosis of PSH, the difference in stoma-related problems remained while no significant difference was seen regarding sexual problems in males.

CONCLUSIONS:

When forming an end colostomy, prophylactic synthetic mesh in a sublay position did not affect global QoL at 1-year follow-up, but stoma-related problems were fewer even in the presence of a clinically diagnosed PSH.

TRIAL REGISTRATION:

NCT00917995.

KEYWORDS:

Mesh; Parastomal hernia; Prophylaxis; Quality-of-life

PMID:
31392405
DOI:
10.1007/s00384-019-03359-2

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center