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Am J Vet Res. 1988 Jul;49(7):1092-7.

Survival of rough and smooth strains of Brucella abortus in bovine mammary gland macrophages.

Author information

1
Department of Veterinary Pathology, College of Veterinary Medicine, Texas A&M University, College Station 77843-4463.

Abstract

Chronic bovine brucellosis is characterized by persistent infection of the mammary gland. The interaction of live Brucella abortus with bovine mammary gland macrophages was studied in vitro. Opsonization of smooth B abortus strain 2308 and rough strain 45/20 was required for phagocytosis by mammary gland macrophages. When opsonized with specific antiserum, strains 2308 and 45/20 stimulated a considerable oxidative burst when phagocytized by mammary gland macrophages. Intracellular survival rates for strain 2308 were significantly higher than those for strain 45/20. After being phagocytized, B abortus localized in phagosomes and phagolysosomes of mammary gland macrophages.

PMID:
3138931
[Indexed for MEDLINE]

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