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Clin Exp Dermatol. 2019 Aug 6. doi: 10.1111/ced.14068. [Epub ahead of print]

Thin vulvar melanoma: a challenging diagnosis. Dermoscopic features of a case series.

Author information

1
Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, Policlinico Sant'Orsola-Malpighi, University of Bologna, Italy.
2
Unit of Dermatology, USL Toscana Centro-Prato Hospital, Prato, Italy.
3
Pathology Division, Istituto Europeo di Oncologia, Milan, Italy.
4
Unità Ginecologia Preventiva, Istituto Europeo di Oncologia, Milan, Italy.
5
Divisione Melanoma, Istituto Europeo di Oncologia, Milan, Italy.

Abstract

BACKGROUND:

Vulvar melanoma (VM) is rare and is often diagnosed late. Dermoscopy may aid in its recognition, differentiating VM from other more common vulvar lesions, such as melanosis and nevi. However, little is known about the dermoscopic features of thin VM.

AIM:

To retrospectively analyze a series of histopathologically diagnosed thin VMs and to highlight their most suggestive dermoscopic features.

METHODS:

A multicentre, retrospective study was conducted, including histopathologically proven thin VMs, either intraepidermal or with Breslow thickness ≤ 0.5 mm, diagnosed in the years 2016-2018. We particularly focused on their dermoscopic characteristics, in order to highlight the most suggestive dermoscopic diagnostic clues.

RESULTS:

Fourteen cases of early stage VM were included, in women with a mean age at diagnosis of 64.86 years. The most frequently affected sites were the labia minora. Eleven cases were unifocal. Dermoscopy most often revealed: structureless areas, grey globules and areas, irregular black-brown dots, blue and white structures, red areas.

CONCLUSIONS:

In our experience, early stage VM often exhibits dermoscopic features which are more typical of thicker cutaneous melanomas. Dermoscopy may provide useful clues for the prompt diagnosis of thin VM. This article is protected by copyright. All rights reserved.

KEYWORDS:

dermoscopy; melanoma; pattern; thin; vulva

PMID:
31389062
DOI:
10.1111/ced.14068

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