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Appl Physiol Nutr Metab. 2019 Aug 6:1-7. doi: 10.1139/apnm-2019-0137. [Epub ahead of print]

Effects of high-intensity interval training and nutrition advice on cardiometabolic markers and aerobic fitness in adolescent girls with obesity.

Author information

1
Department of Pediatric and Adolescent Gynecology, Mother and Child Health Care Institute of Serbia "Dr Vukan Cupic", Radoja Dakica 6-8, 11070 Belgrade, Serbia.
2
Institute for Medical Research, University of Belgrade, Dr Subotica 4, 11000 Belgrade, Serbia.
3
Department of Pulmonology, Mother and Child Health Care Institute of Serbia "Dr Vukan Cupic", Radoja Dakica 6-8, 11070 Belgrade, Serbia.
4
School of Medicine, University of Belgrade, Dr Subotica 8, 11000 Belgrade, Serbia.
5
Department of Endocrinology, Mother and Child Health Care Institute of Serbia "Dr Vukan Cupic", Radoja Dakica 6-8, 11070 Belgrade, Serbia.
6
Institute of Medical Physiology, Faculty of Medicine, University of Belgrade, Visegradska 26, 11000 Belgrade, Serbia.
7
Clinic of Endocrinology, Diabetes and Metabolic Diseases, Faculty of Medicine, University of Belgrade, Dr Subotica 13, 11000 Belgrade, Serbia.

Abstract

The aim of the study was to compare the effects of high-intensity interval training (HIIT) and nutrition advice on cardiometabolic biomarkers, hormonal parameters, and cardiorespiratory fitness in adolescent girls with obesity. Adolescent girls with obesity (n = 44, aged 13-19 years) were randomized into a 12-week intervention as follows: (i) dietary advice and HIIT (n = 22), and (ii) dietary advice only (n = 22). The concentration of biomarkers of inflammation, biochemical and hormonal testing, oral glucose tolerance test, cardiorespiratory fitness, physical activity levels, and nutrition were assessed. After a 3-month intervention, the diet+HIIT group significantly increased insulin sensitivity index (-0.34 ± 1.52 vs. 1.05 ± 3.21; p = 0.001) and work load (0.6 ± 11.3 W vs. 14.6 ± 20.2 W; p = 0.024) and decreased glucose area under the curve (-0.29 ± 4.69 vs. -0.98 ± 4.06; p = 0.040), insulin area under the curve (-9.65 ± 117.9 vs. -98.7 ± 201.8; p = 0.003), and high-sensitivity C-reactive protein (hs-CRP) (0.12 ± 1.92 mg/L vs. -1.47 ± 3.67 mg/L; p = 0.039) in comparison with the diet group. Regarding within-group changes, both groups had significant improvements in body mass index (BMI), BMI-standard deviation score, body fat percentage, and systolic blood pressure. Positive impact on waist circumference, waist circumference/height ratio, diastolic blood pressure, hs-CRP, work load, maximal heart rate, and resting heart rate was observed only after the diet+HIIT intervention. No significant change was noted in peak oxygen uptake, lipid profile, and hormonal parameters between groups after intervention. Novelty HIIT and nutrition advice increased insulin sensitivity and decreased BMI, body fat, systolic blood pressure, and diastolic blood pressure. Nutrition advice decreased BMI, body fat, and systolic blood pressure in adolescent girls with obesity.

KEYWORDS:

HIIT; adolescents; aptitude cardiorespiratoire; cardiorespiratory fitness; cardiovascular risk; hypocaloric diet; insulin sensitivity; obesity; obésité; risque cardiovasculaire; régime hypocalorique; sensibilité à l’insuline

PMID:
31386826
DOI:
10.1139/apnm-2019-0137

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