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Ned Tijdschr Geneeskd. 2019 Aug 6;163. pii: D3758.

[Deep brain stimulation for movement disorders].

[Article in Dutch]

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Amsterdam UMC, locatie AMC, afd. Neurologie, Amsterdam.
Contact: M. Beudel (
UMCG, afd. Neurochirurgie, Groningen.
UMCG, afd. Neurologie, Groningen.


Deep brain stimulation (DBS) is a treatment which uses high-frequency electric stimulation to suppress pathological brain activity. DBS has been applied for over 30 years now, particularly in patients with severe movement disorders, such as Parkinson's disease, dystonia and tremor. Although there is clearly scientific evidence for the effectiveness of DBS in these three movement disorders, the effect size of the treatment remains limited. Furthermore, DBS is not curative and can only be applied in a select subset of patients. In this article, we discuss the key indications and contraindications for DBS, and the outcomes achieved when it is applied in the aforementioned movement disorders. We discuss the most notable controversies and new developments in the field of deep brain stimulation, in order to offer referrers and fellow healthcare professionals an accessible introduction to this mode of therapy.


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