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Complement Ther Clin Pract. 2019 Aug;36:170-175. doi: 10.1016/j.ctcp.2019.07.008. Epub 2019 Jul 19.

Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial.

Author information

1
Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: m-motaharifard@razi.tums.ac.ir.
2
Ziaeian Hospital, School of Medicine, International Campus, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: m.effatpanah@gmail.com.
3
Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: mehrdadkarimi@yahoo.com.
4
Psychiatric Research Center, Roozbeh Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: S.akhond@neda.net.
5
Clinical Research Development Unit-Matini/Kargarnejad Hospital, Kashan University of Medical Sciences, Kashan, Iran. Electronic address: rahimi_136@yahoo.com.
6
Department of Chemistry, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran. Electronic address: Yasrebi.seyedali@gmail.com.
7
Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran. Electronic address: nejatbakhsh@tums.ac.ir.

Abstract

BACKGROUND AND PURPOSE:

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common health disorders among children. Some patients do not respond to methylphenidate or cannot tolerate its side effects. Sweet almond syrup as a Persian Medicine preparation has been used for many years. This study aims to evaluate the efficacy and safety of sweet almond for ADHD children.

MATERIALS AND METHODS:

Fifty children aged 6-14 years with ADHD were recruited to the study. The participants were randomly assigned to two groups to receive either methylphenidate or sweet almond syrup. The outcomes were assessed using the Parent and Teacher ADHD Rating Scale every two weeks for 8 weeks.

RESULTS:

Results showed that the two treatments had similar effects on symptom reduction in ADHD children. No significant differences were observed between the two groups (F=2.3, df=1, p=0.13, F=0.57, df=1, p=0.47).

CONCLUSION:

Sweet almond may be an effective treatment for ADHD children.

KEYWORDS:

DHD; Iranian Traditional Medicine; Persian Medicine; functional food; sweet almond

PMID:
31383435
DOI:
10.1016/j.ctcp.2019.07.008
[Indexed for MEDLINE]

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