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J Surg Oncol. 2019 Sep;120(4):573-577. doi: 10.1002/jso.25626. Epub 2019 Aug 1.

Breast implant-associated anaplastic large cell lymphoma, a systematic review and in-depth evaluation of the current understanding.

Author information

1
Keck School of Medicine of University of Southern California, Los Angeles, California.
2
Department of Plastic and Reconstructive Surgery, University of Southern California, Los Angeles, California.

Abstract

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a T-cell neoplasm that arises in the capsule around breast implants. While an association with implants has been proposed, no causal link has been identified and the pathophysiology and natural history of BIA-ALCL remain unknown. A literature review of 391 articles was performed to assess the current understanding of BIA-ALCL and to provide a balanced and unbiased view of the current controversy surrounding the disease.

KEYWORDS:

BIA-ALCL; breast implants; lymphoma

PMID:
31373010
DOI:
10.1002/jso.25626
[Indexed for MEDLINE]

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