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Indian J Dermatol Venereol Leprol. 2019 Aug 1. doi: 10.4103/ijdvl.IJDVL_588_18. [Epub ahead of print]

Glucagonoma syndrome with atypical necrolytic migratory erythema.

Author information

1
Department of Dermatology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
2
Department of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

Abstract

Necrolytic migratory erythema is most commonly associated with glucagonoma syndrome. We report a rare case of glucagonoma syndrome with necrolytic migratory erythema presenting as pruritic papules and follicular pustules in a 57-year-old woman; showing eosinophilic infiltration on histology. However, the final diagnosis was confirmed by demonstrating neuroendocrine tumour on histopathological examination of the liver metastases. Nutrition therapy was administered as a palliative treatment. This case also highlights the atypical clinical features and nonspecific histology of necrolytic migratory erythema which makes the diagnosis difficult.

KEYWORDS:

Glucagonoma syndrome; necrolytic migratory erythema; nutrition therapy

PMID:
31368453
DOI:
10.4103/ijdvl.IJDVL_588_18
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