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Cureus. 2019 May 30;11(5):e4784. doi: 10.7759/cureus.4784.

A Rare Presentation of Cardiac Aspergilloma in an Immunocompetent Host: Case Report and Literature Review.

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Internal Medicine, University of Massachusetts Medical School - Baystate Medical Center, Springfield, USA.
Internal Medicine, Doctors Hospital / University of Texas Rio Grande Valley, Edinburg, USA.
Internal Medicine, Windsor University School of Medicine, Basseterre, KNA.
Internal Medicine, Kingsbrook Jewish Medical Center, New York, USA.
Psychology, The University of Texas at Austin, Austin, USA.


Cardiac aspergilloma is exceptionally rare with only a handful of cases reported and majority of them being in immunocompromised patients. Here, we present a case of cardiac aspergilloma involving the right and left ventricle in an immunocompetent patient that initially presented with acute limb ischemia. He was later found to have a cardiac mass with histopathological diagnosis confirming Aspergillus species. Despite aggressive medical and surgical interventions, the patient had an unfavorable outcome due to low suspicion of invasive fungal endocarditis given his immunocompetent status. Cardiac aspergilloma should remain in the differential diagnosis of immunocompetent patients as early clinical suspicion will result in early treatment and decreased mortality. Novel therapies are required to decrease mortality in the future from this fatal disease.


aspergilloma; aspergillus; cardiac aspergilloma; cerebral emboli; immunocompetent; infective endocarditis

Conflict of interest statement

The authors have declared that no competing interests exist.

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