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Ophthalmic Plast Reconstr Surg. 2019 Jul 26. doi: 10.1097/IOP.0000000000001434. [Epub ahead of print]

Idiopathic Conjunctival Calcinosis Associated With an Intradermal and Subepithelial Nevus of the Eyelid Margin.

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Departments of Ophthalmology.
Pathology, New York University Langone Medical Center, New York, New York, U.S.A.


A 37-year-old woman underwent excision of a congenital melanocytic nevus of the right lower eyelid margin for cosmetic reasons. She suffered from a severe dry eye syndrome which was partially alleviated with various topical eye drops. Histopathology of the excised tissue displayed flecks of calcium that were present within the immediate subepithelial conjunctival fibrous tissue but not the nevocytes or the cutaneous surface. Unlike calcinosis cutis, wherein calcium is deposited within the cutaneous dermis, calcification of the conjunctival substantia propria is rare and may be related to the dry eye state.

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