Format

Send to

Choose Destination
Cont Lens Anterior Eye. 2019 Jul 26. pii: S1367-0484(18)31032-4. doi: 10.1016/j.clae.2019.07.008. [Epub ahead of print]

Randomised trial of the clinical utility of an eyelid massage device for the management of meibomian gland dysfunction.

Author information

1
Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand.
2
Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand; School of Optometry and Vision Science, New Zealand National Eye Centre, The University of Auckland, New Zealand.
3
Department of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, New Zealand. Electronic address: jp.craig@auckland.ac.nz.

Abstract

PURPOSE:

To compare the single application and two week treatment effects of device-applied (Eyepeace) and manually-applied eyelid massage techniques, as an adjunct to warm compress therapy, on ocular surface and tear film parameters.

METHODS:

Twenty participants (11 females, 9 males; mean age, 27 ± 11 years) with dry eye symptoms were recruited in a two week, investigator-masked, randomised, contralateral-eye trial. Following 10 min of warm compress therapy application (MGDRx EyeBag®) on both eyes, eyelid massage therapy was applied to one eye (randomised) by device, and to the fellow eye by manual eyelid massage, once daily for 14 days. Ocular surface and tear film measurements were conducted at baseline, and 15 min post-application by a clinician, then again after 14 days of self-administered daily treatment at home.

RESULTS:

Baseline clinical measurements did not differ between the treatment groups (all p > 0.05). Following two weeks of treatment, tear film lipid layer grade improved significantly with device massage (p = 0.008), and was marginally greater than manual massage by less than 1 grade (p = 0.03). Although immediate post-treatment improvements in tear film stability were observed in both groups (both p < 0.05), no significant long-term cumulative effects or inter-treatment differences in stability measures were detected (all p > 0.05). Visual acuity, tear meniscus height, conjunctival hyperaemia, ocular surface staining, and meibomian gland dropout did not change during the treatment period (all p > 0.05).

CONCLUSIONS:

Two weeks of treatment with the eyelid massage device, as an adjunct to warm compress therapy, effected marginally greater improvements in tear film lipid layer thickness than the conventional manual technique, which were statistically but not clinically significant. Future parallel group trials with longer treatment periods and a greater range of disease severity are required.

KEYWORDS:

Dry eye; Eyelid massage; Meibomian gland dysfunction; Meibum expression; Ocular surface; Tear film

PMID:
31358441
DOI:
10.1016/j.clae.2019.07.008

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center