Format

Send to

Choose Destination
See comment in PubMed Commons below
Am J Vet Res. 1988 Jun;49(6):929-32.

Minimum anesthetic dose and cardiopulmonary dose response for halothane in chickens.

Author information

1
Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706.

Abstract

The minimum anesthetic dose (MAD) and the cardiopulmonary dose-response for halothane were determined in male chickens. The MAD for halothane was 0.85 +/- 0.09% (mean +/- SD), with a range of 0.75% to 0.98%. There was a significant (P less than 0.002) positive correlation between increasing concentrations of halothane and PaCO2, and significant negative correlations of halothane concentration with respiratory rate (P less than 0.04), arterial blood pH (P less than 0.008), and mean arterial blood pressure P less than 0.008). A significant correlation was not found between halothane concentration and heart rate or arterial blood bicarbonate concentration. It was concluded that the MAD for halothane in chickens is similar to values for minimum alveolar concentrations of halothane in mammalian species, and that there is substantial dose-dependent depression of cardiopulmonary function in chickens.

PMID:
3135771
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center