Format

Send to

Choose Destination
Emerg Med Pract. 2019 Aug;21(8):1-28. Epub 2019 Aug 1.

Emergency department management of patients taking direct oral anticoagulant agents.

Author information

1
Assistant Professor, Emergency Medicine and Critical Care, Icahn School of Medicine at Mount Sinai, New York, NY.
2
Department of Emergency Medicine and Critical Care, Icahn School of Medicine at Mount Sinai, New York, NY.

Abstract

Direct oral anticoagulant (DOAC) agents have become commonly used over the last 9 years for treatment and prophylaxis for thromboembolic conditions, following approvals by the United States Food and Drug Administration. These anticoagulant agents, which include a direct thrombin inhibitor and factor Xa inhibitors, offer potential advantages for patients over warfarin; however, bleeding emergencies with DOACs can present diagnostic and therapeutic challenges because, unlike traditional anticoagulants, their therapeutic effect cannot be easily monitored directly with common clotting assays. This review examines the growing body of evidence on the uses and risks of DOACs in the emergency department, including initiation of therapy and reversal strategies.

PMID:
31339254

Supplemental Content

Full text links

Icon for EB Medicine
Loading ...
Support Center