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Indian J Ophthalmol. 2019 Aug;67(8):1374-1377. doi: 10.4103/ijo.IJO_1745_18.

Endocrine mucin-producing sweat gland carcinoma (EMPSGC) of the eyelid: Clinicopathologic features, immunohistochemical findings and review of literature.

Author information

1
National Reporting Centre for Ophthalmic Pathology, Centre for Sight, Hyderabad, India.
2
Oculoplastics, Facial Aesthetics and Ocular Oncology, Centre for Sight, New Delhi, India.
3
Ophthalmic Plastic Surgery and Ocular Oncology, Centre for Sight, Hyderabad, India.
4
Oculoplastics, Facial Aesthetics and Ocular Oncology, Centre for Sight, Jaipur, Rajasthan, India.

Abstract

Sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both, ophthalmologists and pathologists. Endocrine, mucin producing sweat gland carcinoma (EMPSGC), considered to be analogous to the solid papillary mammary carcinoma is one such tumor. It usually affects elderly, is more frequent in women and has a predilection for skin of the eyelid. Although it has an indolent clinical course, EMPSGC is believed to be a precursor of the invasive mucinous carcinoma and has a potential for local recurrence. We report a series of 10 biopsy-proven EMPSGCs with their immunohistochemical features and review the literature.

KEYWORDS:

Carcinoma; endocrine; eyelid; mucin; sweat gland

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