Format

Send to

Choose Destination
Pediatr Pulmonol. 2019 Oct;54(10):1610-1616. doi: 10.1002/ppul.24435. Epub 2019 Jul 21.

Spanish multicentre study on morbidity and pathogenicity of tracheal bronchus in children.

Author information

1
Division of Pediatrics, Paediatric Pneumology Unit, University Clinic Hospital, Valencia, Spain.
2
Division of Pediatrics, Regional University Hospital of Málaga, Málaga, Spain.
3
Paediatric Airway Unit, University Hospital 12 de Octubre, Madrid, Spain.
4
Division of Pediatrics, Virgen de la Arrixaca Hospital, Murcia, Spain.
5
Division of Pediatrics, La Paz University Hospital, Madrid, Spain.
6
Division of Pediatrics, Niño Jesús Hospital, Madrid, Spain.
7
Division of Pediatrics, Son Espases Hospital, Palma, Spain.
8
Division of Pediatrics, Reina Sofia Children's University Hospital, Córdoba, Spain.
9
Division of Pediatrics, Cruces University Hospital, Bilbao, Spain.
10
Division of Pediatrics, Parc Taulí Hospital, Barcelona, Spain.
11
Division of Pediatrics, Virgen Macarena Hospital, Sevilla, Spain.
12
Division of Pediatrics, Virgen del Rocío Hospital, Sevilla, Spain.
13
Division of Pediatrics, Torrecárdenas Hospital, Almería, Spain.
14
Division of Pediatrics, University of Valencia, Valencia, Spain.

Abstract

Tracheal bronchus (TRB) has been generally considered an anatomical variant of the tracheobronchial tree without a precise pathological effect. Its prevalence is estimated to be between 0.2% to 3% of all children undergoing bronchoscopy and scientific information has been limited to case reports or small case series. Our working hypothesis was that TRB could trigger by itself recurrent or persistent respiratory symptoms. The objective of this retrospective and multicentre study of children with a diagnosis of TRB, coming from the main paediatric pulmonology units of Spain, was to determine the anatomical and clinical characteristics, including comorbidities, of TRB in childhood and their impact in the patients' clinical outcomes. One hundred thirty-three patients from 13 institutions were included in the study. Mean diagnostic age was 3.4 years and flexible bronchoscopy was the initial diagnostic method in 85% of cases. All TRB were located on the right wall of the trachea: 76% in the lower third and 24% in the carina. The most common clinical manifestations were obstructive bronchitis (53.3%) and recurrent pneumonia (46.6%), usually affecting the right upper lobe. Regarding associated anomalies, 33% had tracheomalacia, 32% congenital cardiovascular malformations, 28% gastroesophageal reflux, 22.5% congenital tracheal stenosis, and 8.3% Down syndrome. This series appears to be the most extensive published to date addressing this topic and, according to our data, TRB does not appear to be a mere incidental finding but is more likely linked to a wide range of congenital anomalies and contributes by itself to the recurrent respiratory symptomatology that these children exhibit.

KEYWORDS:

bronchoscopy; children; lung development; trachea; tracheal bronchus

PMID:
31328420
DOI:
10.1002/ppul.24435

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center