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Postepy Dermatol Alergol. 2019 Apr;36(2):184-191. doi: 10.5114/ada.2019.84594. Epub 2019 May 14.

Clinical characteristics and epidemiology of chronic urticaria: a nationwide, multicentre study on 1091 patients.

Author information

1
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Wroclaw, Poland.
2
Department of Dermatology, University of Rzeszow, Rzeszow, Poland.

Abstract

Introduction:

Urticaria is one of the most common skin diseases. Depending on the length of symptoms, acute (lasting less than 6 weeks) and chronic urticaria (CU) (> 6 weeks) are distinguished. According to the current European guidelines, CU is divided into inducible urticaria (IU) and chronic spontaneous urticaria (CSU).

Aim:

To assess the epidemiology and clinical characteristics of CU in Poland.

Material and methods:

This was a nationwide, multicentre, cross-sectional, questionnaire-based study performed under the auspices of the Polish Dermatological Society. A total of 102 physicians (dermatologists and allergists) recruited 1091 patients suffering from CU.

Results:

Among 1091 adults with CU, IU was found in 35.1% (n = 383) of patients and CSU was responsible for 61.1% (n = 667) of CU cases. The remaining patients (n = 41, 3.8%) suffered from both, IU and CSU. Persons with CSU were twice more likely to report family history of urticaria than those with IU (12.1% vs. 6.0%, p = 0.001). Generalized eruptions of wheals predominated in CSU (generalized wheals: 57.9%, localized wheals: 42.1%), whereas wheals localized in particular body areas were found more commonly in IU (generalized wheals: 45.2%, localized wheals: 54.8%, p < 0.001). The CU was the cause of absenteeism in almost every fifth patient suffering from this disease.

Conclusions:

The CSU is about twice as frequent cause of CU as compared to IU. The treatment of CU is a major challenge for physicians of various specialties and the treatment choice is closely associated with the specialist knowledge of current treatment guidelines.

KEYWORDS:

allergic diseases; chronic spontaneous urticaria; inducible urticaria

Conflict of interest statement

This study was supported by an educational grant provided by Novartis Poland.

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