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Nat Prod Res. 2019 Jul 17:1-6. doi: 10.1080/14786419.2019.1641813. [Epub ahead of print]

Lindermyrrhin, a novel 3,4-dihydroisocoumarin from Lindera myrrha roots.

Author information

a Department for Management of Science and Technology Development , Ton Duc Thang University , Ho Chi Minh City , Vietnam.
b Faculty of Applied Sciences , Ton Duc Thang University , Ho Chi Minh City , Vietnam.
c Center of Excellence in Natural Products Chemistry, Department of Chemistry, Faculty of Science , Chulalongkorn University , Bangkok , Thailand.
d Institute of Environment-Energy Technology, Sai Gon University , Ho Chi Minh City , Vietnam.
e Faculty of Science and Technology , Thammasat University Lampang Campus , Lampang , Thailand.
f Institute of Tropical Biology, Vietnam Academy of Science and Technology , Ho Chi Minh City , Vietnam.
g NTT-High tech Institute , Nguyen Tat Thanh University , Ho Chi Minh City , Vietnam.


A novel 3,4-dihydroisocoumarin, lindermyrrhin (1), along with three known compounds, quercetin (2), northalifoline (3) and N-formyl-laurolitsine (4) were isolated from the roots of Lindera myrrha. The structure of compound 1 was identified by interpretation of their spectroscopic data as well as comparison with those reported in the literature. The novel compound 1 represents the first 3,4-dihydroisocoumarin bearing a 2-hydroxyisopropyl substituent at C-3.


3,4-dihydroisocoumarin; Lauraceae; Lindera myrrha; lindermyrrhin

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