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Catheter Cardiovasc Interv. 2019 Jul 16. doi: 10.1002/ccd.28399. [Epub ahead of print]

Use of "super-glue" to seal a perforation during chronic total occlusion coronary intervention and the potential to "unglue" it.

Author information

1
Division of Cardiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
2
Division of Cardiology, Central Arkansas Veterans Health Care System, Little Rock, Arkansas.
3
Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, Arkansas.

Abstract

Coronary perforation remains a dreaded complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI). We present a case of successful CTO recanalization complicated by a perforation treated by n-butyl-cyanoacrylate (medical "super-glue"). We also present an in vitro experiment showing that a glue plug in a plastic tube can acutely be passed by a low tip load guide wire and undergo balloon angioplasty recreating a lumen. These results suggest that n-butyl-cyanoacrylate glue may be an alternative for treating perforation during CTO PCI with the possibility of recanalizing the vessel through the glue plug at a later time.

KEYWORDS:

chronic total occlusion; medical glue; percutaneous coronary intervention; perforation

PMID:
31313466
DOI:
10.1002/ccd.28399

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