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Bioinformation. 2019 Jun 15;15(6):425-429. doi: 10.6026/97320630015425. eCollection 2019.

Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora.

Author information

1
Department of Biochemistry and Bioinformatics, Karpagam Academy of Higher Education, Coimbatore, Tamilnadu, India 641 02.
2
Cancer Biology Department, Mitra RxDx Inc. Woburn MA 01801, USA.

Abstract

Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders.

KEYWORDS:

GC-MS analysis; Tylophora pauciflora; bioactive compounds; ethanolic extract

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