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Pediatr Infect Dis J. 2019 Aug;38(8):e180-e183. doi: 10.1097/INF.0000000000002279.

Respiratory Virus Epidemiology Among US Infants With Severe Bronchiolitis: Analysis of 2 Multicenter, Multiyear Cohort Studies.

Author information

1
From the Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
2
National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
3
Department of Infectious Disease, Arnold Palmer Hospital for Children, Orlando, Florida.
4
Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
5
Departments of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, Texas.

Abstract

In 2 multicenter cohort studies of 2912 infants hospitalized for bronchiolitis during 2007-2014, the 5 most common pathogens were RSV (76.5%), rhinovirus (23.8%), coronavirus (6.9%), adenovirus (6.4%) and human metapneumovirus (6.0%). Hospitalization months significantly differed for these common pathogens (P ≤ 0.01), except for coronavirus (P = 0.30). There was a significant heterogeneity in temporal patterns by region in RSV-A and -B (both P < 0.001).

PMID:
31306402
PMCID:
PMC6636850
[Available on 2020-08-01]
DOI:
10.1097/INF.0000000000002279

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