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Nicotine Tob Res. 2019 Jul 11. pii: ntz114. doi: 10.1093/ntr/ntz114. [Epub ahead of print]

Electronic Cigarette Use and Cigarette Abstinence Over Two Years among U.S. Smokers in the Population Assessment of Tobacco and Health Study.

Author information

1
Tobacco Research and Treatment Center, Division of General Internal Medicine, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
2
Harvard Medical School, Boston, Massachusetts.

Abstract

INTRODUCTION:

Electronic cigarettes (e-cigarettes) could benefit public health if they help current smokers to stop smoking long-term, but evidence that they do so is limited. We aimed to determine the association between e-cigarette use and subsequent smoking cessation in a nationally representative cohort of U.S. smokers followed for two years.

METHODS:

We analyzed data from adult cigarette smokers in Waves 1 to 3 of the Population Assessment of Tobacco and Health (PATH) Study. The primary exposure was e-cigarette use at Wave 1. The primary outcome was prolonged cigarette abstinence, defined as past 30-day cigarette abstinence at Waves 2 and 3 (1 and 2-year follow-up).

RESULTS:

Among Wave 1 cigarette smokers, 3.6% were current daily e-cigarette users, 18% were current non-daily e-cigarette users, and 78% reported no current e-cigarette use. In multivariable adjusted analyses, daily e-cigarette use at Wave 1 was associated with higher odds of prolonged cigarette smoking abstinence at Waves 2 and 3 compared to non-use of e-cigarettes (11% vs 6%, AOR 1.77, 95% CI 1.08-2.89). Non-daily e-cigarette use was not associated with prolonged cigarette smoking abstinence. Among Wave 1 daily e-cigarette users who were abstinent from cigarette smoking at Wave 3, 63% were using e-cigarettes at Wave 3.

CONCLUSIONS:

In this longitudinal cohort study of U.S. adult cigarette smokers, daily but not non-daily e-cigarette use was associated with higher odds of prolonged cigarette smoking abstinence over two years, compared to no e-cigarette use. Daily use of e-cigarettes may help some smokers to stop smoking combustible cigarettes.

IMPLICATIONS:

Electronic cigarettes (e-cigarettes) could benefit public health if they help current smokers to stop smoking long term, but evidence that they do so, particularly from observational "real world" studies, is limited. In this nationally-representative longitudinal cohort study of U.S. adult cigarette smokers, daily e-cigarette use, compared to no e-cigarette use, was associated with a 77% increased odds of prolonged cigarette smoking abstinence over the subsequent two years. Regular use of e-cigarettes may help some smokers to stop smoking combustible cigarettes.

PMID:
31298296
DOI:
10.1093/ntr/ntz114

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