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Indian J Nucl Med. 2019 Jul-Sep;34(3):235-236. doi: 10.4103/ijnm.IJNM_157_18.

131I Uptake in Bronchiectasis Detected by Single Photon Emission Computed Tomography/Computed Tomography during Follow-up of Thyroid Cancer.

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Department of Nuclear Medicine and Theranostics, "Mariano Santo" Hospital, 87100, Cosenza, Italy.
Department of Infectious and Tropical Diseases, "St. Annunziata" Hospital, 87100, Cosenza, Italy.
Department of Biomedicine and Prevention, University "Tor Vergata", Rome, Italy.
Department of Nuclear Medicine and Molecular Imaging, IRCCS INM Neuromed, Pozzilli (IS), Italy.


During follow-up of thyroid cancer, 131I whole-body scan showed intense tracer uptake in the right hemithorax of a patient previously submitted to thyroidectomy and radioiodine therapy for differentiated thyroid cancer. Thyroglobulin was undetectable at the time of the scan. Single-photon emission computed tomography/computed tomography (SPECT/CT) of the thorax correctly identified widespread bronchiectasis 131I-avid in the middle lobe of the right lung. After bronchoalveolar lavage, a bronchial specimen was positive for Mycobacterium avium infection. Hybrid imaging with SPECT/CT allowed to correctly identify a false-positive case of 131I uptake due to inflammation in a single diagnostic session, minimizing patient discomfort or misdiagnoses.


131I; bronchiectasis; pitfalls; single-photon emission computed tomography/computed tomography; uptake

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